In vitro chemosensitivity testing of primary and recurrent breast carcinomas and its clinical significance / 华中科技大学学报（医学）（英德文版）
Journal of Huazhong University of Science and Technology (Medical Sciences)
; (6): 683-7, 2008.
Article
en En
| WPRIM
| ID: wpr-635038
Biblioteca responsable:
WPRO
ABSTRACT
In this study, in vitro chemosensitivity testing was conducted on primary cultured breast cancer cells from 96 patients with breast cancer, and the results showed that the cells from a few patients with primary breast cancer developed multidrug resistance (MDR) prior to the first chemotherapy exposure. All the cells from the recurrent cancer patients had MDR. The findings suggested that patients having MDR would benefit from high-dose chemotherapy (HDC) regimens. In vitro chemosensitivity screening, which was aimed at improving the therapeutic efficacy and minimizing side effects, helps in choosing individualized treatment for breast cancer.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Neoplasias de la Mama
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Ensayos de Selección de Medicamentos Antitumorales
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Células Tumorales Cultivadas
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Resistencia a Múltiples Medicamentos
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Resistencia a Antineoplásicos
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Recurrencia Local de Neoplasia
/
Antineoplásicos
Idioma:
En
Revista:
Journal of Huazhong University of Science and Technology (Medical Sciences)
Año:
2008
Tipo del documento:
Article