Childhood disabling Pansclerotic Morphoea complicated by leg ulcers, contractures and gangrene
Malaysian Journal of Dermatology
; : 25-30, 2010.
Article
en En
| WPRIM
| ID: wpr-626043
Biblioteca responsable:
WPRO
ABSTRACT
Disabling pansclerotic morphoea of childhood is a subset of localized scleroderma. It is a rare disease in both the adult and paediatric population. E t i o l ogical factors are unknown although autoimmune, infectious, genetic and environmental factors have been postulated. Sclerotic plaques predominantly affect the scalp, face, trunk and extensor surfaces of limbs, leaving fingertips and toes uninvo l ved. The absence of Raynaud’s phenomenon, dysphagia, visceral involvement and certain laboratory derangements diff e r e n t i a t e systemic sclerosis and disabling pansclerotic morphoea of childhood. Diagnosis can be supported by histology. There are seve r a l management options including topical, systemic and phototherapy.
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Base de datos:
WPRIM
Idioma:
En
Revista:
Malaysian Journal of Dermatology
Año:
2010
Tipo del documento:
Article