Correlation of P53 expression with proliferation and apoptosis in gestational trophoblastic tumor / 基础医学与临床
Basic & Clinical Medicine
; (12)2006.
Article
en Zh
| WPRIM
| ID: wpr-590236
Biblioteca responsable:
WPRO
ABSTRACT
Objective To elucidate the features of the expression of P53,proliferation and apoptosis in gestational trophoblastic tumor(GTT).Methods Ten cases of normal placenta,10 cases of complete hydatidiform mole(CM),20 cases of invasive hydatidiform mole(IM)and 19 cases of choriocarcinoma(CCA)paraffin-embedded tissues were studied.P53 and PCNA were detected with immunohistochemistry,apoptosis was detected with terminal deoxy-nucleotidyl transferase-mediated dUTP-biotin nick end labeling(TUNEL).Results In NP,CM,IM and CCA,the P53 indexes(P53-Ⅰ)were 4.12%,21.68%,39.61% and 27.39% respectively with significant differences among them(P
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Basic & Clinical Medicine
Año:
2006
Tipo del documento:
Article