Comparison of Antitumor Effect in vivo between Transmembrane TNF-? and Secretory TNF-? / 中国肿瘤生物治疗杂志
Chinese Journal of Cancer Biotherapy
; (6)1996.
Article
en Zh
| WPRIM
| ID: wpr-581925
Biblioteca responsable:
WPRO
ABSTRACT
Objective: To study the antitumor effects of transmembrane TNF-? and secretory TNF-? in vivo. Methods: Three types of TNF-? cDNA plasmids (wild type TNF-?; transmembrane TNF-? mutant; secretory TNF-? mutant) were directly injected into tumor-tearing mice. Results: The three types of TNF-? could be expressed by tumor cells and all of them could inhibit evidently the rate of tumor growth. The tumor regression after treatment with transmembrane TNF-? mutant at the early stage was more significant than that with the other two types of TNF-?( P
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Cancer Biotherapy
Año:
1996
Tipo del documento:
Article