EXPERIMENTAL STUDIES ON ANTITHROMBOSIS OF EICOSAPENTAENOIC ACID / 中国海洋药物
Chinese Journal of Marine Drugs
; (6)1994.
Article
en Zh
| WPRIM
| ID: wpr-581673
Biblioteca responsable:
WPRO
ABSTRACT
The effects of eicosapentaenoic acid (EPA) on experimental thrombosis and its mechanism were studied. The results showed that eicosapentaenoic acid had a significant antithrombolic effect both in vivo and in vitro . EPA also had a fibrinolytic activity and can shorten euglobulin lysis time. Our studies also showed that EPA can inhibit platelet aggregation in rats. The plasma concentration of 6-keto-PGF1a and TXB2 was measured by radioimmunoassay. The results showed that EPA can reduce the contents of TXB2 and raise 6-keto-PGF1a/TXB2 ratio.
Texto completo:
1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Marine Drugs
Año:
1994
Tipo del documento:
Article