Experimental study on anti-tumor efficacy of Shengmai Injection combined with Oxaliplatin / 中成药
Chinese Traditional Patent Medicine
; (12)1992.
Article
en Zh
| WPRIM
| ID: wpr-575081
Biblioteca responsable:
WPRO
ABSTRACT
AIM: To observe the changes in tumor-weight-inhibiting rates,immunological function,liver and renal function and the blood cell in the peripheral blood after administration of Shengmai Injection combined with chemotherapeutic agent,Oxaliplatin. METHODS: Hepatoma 22 tumor bearing mice models were established and then divided randomly into five groups,including control group,Oxaliplatin group,Shengmai Injection(high,middle and low dose) combined with Oxaliplatin groups.Each group had 10 mice.The five groups were injected introperitoneally with same amount of 5% glucose injection,Oxaliplatin 6 mg/kg and Shengmai Injection(14 mL/kg,7 mL/kg and 3.5 mL/kg) plus Oxaliplatin 6 mg/kg respectively,once a day for 14 days. After that,mice in the five groups were all killed after being anesthetized and the tumor-weight-inhibiting rates and the index of immunological function,liver and renal function and the blood cell in the peripheral blood were observed. RESULTS: (1) The tumor-weight-inhibiting rates were higher in each Shengmai Injection plus Oxaliplatin group than that in the Oxaliplatin group (P
Texto completo:
1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Traditional Patent Medicine
Año:
1992
Tipo del documento:
Article