Effect of the total saponins of Rubus parvifolius on the intracellular free calcium in ischemic hippocampal neurons / 中国药理学通报
Chinese Pharmacological Bulletin
; (12)2003.
Article
en Zh
| WPRIM
| ID: wpr-561872
Biblioteca responsable:
WPRO
ABSTRACT
Aim To study the effect of the total saponins of Rubus parvifolius(TSRP)on the intracellular free calcium levels in ischemic hippocampus neurons.Methods The cytosolic free calcium concentration in ischemic hippocampal neurons was measured by using Ca2+-sensitive fluorescent probe fluo-2/AM with a laser scanning confocal microscope.Results Application of TSRP inhibited free intracellular calcium in ischemic hippocampus neurons in a concentration-dependent manner.Conclusions These results suggest that TSRP might protect hippocampus neurons via attenuating calcium overload induced by ischemia.
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Pharmacological Bulletin
Año:
2003
Tipo del documento:
Article