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Efficacy and safety of diclofenac sodium paste in the treatment of primary osteoarthritis of the knee / 中国基层医药
Article en Zh | WPRIM | ID: wpr-559299
Biblioteca responsable: WPRO
ABSTRACT
Objective To assess the efficacy and safety of diclofenac sodium paste in the treatment of primary osteoarthritis(OA).Methods 54 patients with primary OA were divided into two groups.The experiment group received diclofenac sodium paste.The control group received diclofenac sodium(votalin) emulgel.Patient global assessment and topical pain assessment,physician global assessment and topical pain assessment were wrote down at baseline and after final application.Safety was assessed by evaluation of adverse events,vital signs,and irritation at the application site.Results There were no significant difference between experiment group and control group in patient global assessment,patient pain assessment,physician global assessment,and physician pain assessment.No serious gastrointestinal or renal adverse events were reported or detected by means of laboratory testing.Conclusion Diclofenac sodium paste is effective and safe in the treatment of primary OA.
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Texto completo: 1 Base de datos: WPRIM Idioma: Zh Revista: Chinese Journal of Primary Medicine and Pharmacy Año: 2006 Tipo del documento: Article
Texto completo: 1 Base de datos: WPRIM Idioma: Zh Revista: Chinese Journal of Primary Medicine and Pharmacy Año: 2006 Tipo del documento: Article