Pathophysiology and Apoptosis in Ischemic Stroke / 国际脑血管病杂志
Article
en Zh
| WPRIM
| ID: wpr-557858
Biblioteca responsable:
WPRO
ABSTRACT
Ischemic stroke is a very complex disorder with many intracellular and extracellular factors such as excitatory amino acids, free radicals, calcium overload, apoptotic genes and inflammation involved in its pathophysiological mechanisms. It has been reported that neuronal death mainly derives from necrosis and/or apoptosis after cerebral ischemia. Those neurons in the ischemic core usually suffer from necrosis, however, apoptosis (also referred to as delayed neuronal death) occurs in the ischemic penumbra, which has been the major therapeutic target in the ischemic stroke.
Texto completo:
1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
International Journal of Cerebrovascular Diseases
Año:
2006
Tipo del documento:
Article