THE IMMUNOLOGIC PROTECTION OF SELENIUM ON GASTRIC MUCOSAL LESIONS OF MICE INFECTED BY HELICOBACTER PYLORI / 营养学报
Acta Nutrimenta Sinica
; (6)2004.
Article
en Zh
| WPRIM
| ID: wpr-557390
Biblioteca responsable:
WPRO
ABSTRACT
Objective: To study the immunologic protection of selenium on gastric mucosal lesions of BALB/C mice infected by Helicobacter pylori (HP). Method:The model was built by ig HP in BALB/C mice and then effects of selenium on gastric mucosal lesions and the CD4、CD8 cells were observed.HP was examined by both of bacterial culture and rapid usease test (RUT). Results:1.0 ?g/g bw selenium could effectively prevent gastric mucosal damages induced by HP. HP could decreased the ratio of CD4 to CD8,but selenium could enhance the activity of CD4 cell and increase the ratio. Conclusion: Se can effectively prevent the gastric mucosal damages of mice infected by HP. One of the mechanisms is that Se can enhance the CD4 activity and increase CD4 /CD8.
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Acta Nutrimenta Sinica
Año:
2004
Tipo del documento:
Article