EXPERIMENTAL OBSERVATION FOR METABOLIC CHANGES IN GLUCOSE AND LACTIC ACID IN BIPEDICLED SEPARATION DELAYED FLAP / 解放军医学杂志
Article
en Zh
| WPRIM
| ID: wpr-552366
Biblioteca responsable:
WPRO
ABSTRACT
Bi-polar,bi-pedicled separation delayed flaps were designed on the backs of New Zealand rabbits with the application of a medical silicon membrane as the separation material. Values of glucose and lactic acid, PtcO 2 were measured separately at proximal,middle and distal areas of the flaps after the distal pedice was cut at 0,1,4,7,14,21 days,respectively, after the formation of flaps. After flap delaying,PtcO 2 in separated flap was always lower than that of the mormal control,accompanied with glucose decrease and lactic acid increase, although there were significant differences in different areas of the flap. The survived area of the flap increased after 7 days. Furthermore,all the length of the flap survived after 21 days,although the level of glucose in the flap was still lower and lactic acid was still higher.The results suggested that by separation and delaying the flap may adapt gradually to hypoxia via lowered metabolism.For flap survival,the threshold value of glucose in flap is 0 01mmol/L , lactic acid is 0 47mmol/L,and PtcO 2 is 3mmHg .
Texto completo:
1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
Medical Journal of Chinese People's Liberation Army
Año:
2001
Tipo del documento:
Article