Can Carbohydrate-Deficient Transferrin (CDT) Reflect Alcohol Consumption in Korean Male Drinkers?
Journal of the Korean Academy of Family Medicine
; : 451-455, 2005.
Article
en Ko
| WPRIM
| ID: wpr-55133
Biblioteca responsable:
WPRO
ABSTRACT
BACKGROUND: It has been suggested that CDT is a potential biological marker in the Western countries to reflect the degree of past alcohol consumption. This study was performed to compare CDT, AST (aspartate transaminase), ALT (alanine transaminase), and GGT (gamma- glutamyl transferase) as a biological marker reflecting drinking amounts in Korean patients. METHODS: The 25 males with moderate drinking(21 drinks/week) were studied for the relationships between their weekly drinking amount and the blood levels of CDT, AST, ALT, and GGT. RESULTS: Only CDT was significantly correlated (P=0.001) with weekly drinking amount among heavy drinkers, while both CDT (P=0.029) and GGT (P=0.000) were significantly correlated in moderate drinkers. Stepwise multiple regression revealed that GGT had R2 of 49.1% in moderate drinkers and CDT had R2 of 38.9% in heavy drinkers for the weekly drinking amount. CONCLUSION: The results described above suggested that CDT can be a potential biological marker for the purpose of quantitative monitoring the drinking behavior of heavy drinkers in Korea.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Consumo de Bebidas Alcohólicas
/
Transferrina
/
Biomarcadores
/
Ingestión de Líquidos
/
Conducta de Ingestión de Líquido
/
Corea (Geográfico)
Límite:
Humans
/
Male
País/Región como asunto:
Asia
Idioma:
Ko
Revista:
Journal of the Korean Academy of Family Medicine
Año:
2005
Tipo del documento:
Article