Assay of antigens with anti-lung cancer McAb 3C_9 and preliminary evaluation of serological diagnosis for lung cancer / 第三军医大学学报
Journal of Third Military Medical University
; (24)1984.
Article
en Zh
| WPRIM
| ID: wpr-551103
Biblioteca responsable:
WPRO
ABSTRACT
The antigens(3C9Ag)which could be recognized by the anti-lung cancer monoclonal antibody 3Ca were assayed with BA-ELISA immunobinding inhibition test in 50 lung cancer patients,21 patients with non-cancerous pulmonary diseases and 40 normal subjects.Meanwhile radioimmunoassay was used to determine serum CEA.It was found that the sensitivity,specificity and accuracy for 3C9Ag to diagnose lung cancer were 76%,90.5% and 80.3% respectively.Much higher positive rates could be found in NSCLC patients and in those with stage Ⅱ or Ⅲ cancer.3CsAg was superior to CEA in its sensitivity and accurracy.Combined assay with 3C9Ag and CEA could increase the positive rate.
Texto completo:
1
Base de datos:
WPRIM
Tipo de estudio:
Diagnostic_studies
Idioma:
Zh
Revista:
Journal of Third Military Medical University
Año:
1984
Tipo del documento:
Article