First-phase insulin secretion and its components in the first-degree relatives of type 2 diabetics / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
; (12)2001.
Article
en Zh
| WPRIM
| ID: wpr-540244
Biblioteca responsable:
WPRO
ABSTRACT
Objective To investigate the changes of first-phase insulin secretion and its components in the first-degree relatives of Chinese type 2 diabetics with normal glucose tolerance and their correlation with type 2 diabetes. Methods The first-degree relatives of type 2 diabetes (Group B, n=35), newly diagnosed type 2 diabetic patients (Group C, n=35) and health subjects (Group A, n=21) were recruited. Immune reactive insulin (IRI), proinsulin (PI), and true insulin (TI) were determined during intravenous glucose tolerance test (IVGTT) in each subjects. IRI was determined with radioimmunoassay kit, while PI and TI with ELISA kits. Results (1) For the fasting sera, the levels of IRI and PI showed significant differences (both P
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Endocrinology and Metabolism
Año:
2001
Tipo del documento:
Article