The changes of Endothelin-1 and tumor necrosis factor-? in the congestive heart failure and the intervention role of vitamin E and vitamin C / 中国综合临床
Clinical Medicine of China
; (12)2001.
Article
en Zh
| WPRIM
| ID: wpr-536221
Biblioteca responsable:
WPRO
ABSTRACT
Objective To study the level changes of tumor necrosis factor ? (TNF ?)and endothelin 1 (ET 1) and the intervention role of vitamin E and vitamin C in the patients with congestive heart failure (CHF).Methods 65 cases of heart failure were randomized into A group of 32 cases and B group of 33 cases.A group were given cardiotonic,diuretic and extending blood vessel drugs;B group were given 200 mg vitamin E once a day and 200 mg vitamin C three times a day,in the duration of two weeks,besides the medications administered to A group.Specific radioimmunoassay and double antibody sandwich ELISA were used to measure the concentrations of TNF ? and ET 1 of 65 cases with heart failure and 32 healthy subjects.Results The TNF ? and ET 1 levels of congestive heart failure patients were significantly higher than those in the control group (P
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Base de datos:
WPRIM
Tipo de estudio:
Clinical_trials
Idioma:
Zh
Revista:
Clinical Medicine of China
Año:
2001
Tipo del documento:
Article