Clinical Research of Therapeutic Drug Monitoring for CsA in Allogeneic Hematopoietic Stem Cell Transplantation / 中国药房
China Pharmacy
; (12)2001.
Article
en Zh
| WPRIM
| ID: wpr-530368
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE:To explore the clinical role of two-hour(C2)of CsA in allogeneic hematopoietic stem cell transplantation.METHODS:The whole blood CsA concentration of 9 patients of C0 and 12 of C2 were determined by FPIA method . RESULTS: The satisfactory immunosuppressive concentration was found as follow: C0 was 200～400 ?g?L-1and C2 was 500～700 ?g?L-1.Both C0 and C2 could predict the acute rejection and side-effects,but C2 is more effective.CONCLUSION:The factors that affect the whole blood concentration of CsA were complex. CsA blood concentration monitoring can be used to guide rational use of CsA,but C2 is more effective than C0.
Texto completo:
1
Base de datos:
WPRIM
Tipo de estudio:
Prognostic_studies
Idioma:
Zh
Revista:
China Pharmacy
Año:
2001
Tipo del documento:
Article