Study on stained elastic fibers and expression of collagen type Ⅳ,CD44v6 with metastasis of lung adenocarcinoma / 中国医师杂志
Journal of Chinese Physician
; (12)2000.
Article
en Zh
| WPRIM
| ID: wpr-526088
Biblioteca responsable:
WPRO
ABSTRACT
Objective To study the expression of elastic fibers,Collagen type Ⅳ and CD44v6 in the metastasis of the pulmonary adenocarcinoma.Methods In paraffin-embedded specimens from 56 cases of pulmonary adenocarcinoma,the elastic fibers were stained with histochemical method and the expressions of collagen type Ⅳ and CD44v6 were detected with immunohistochemical method.Results The positive expression rates of elastic fibers,collagen type Ⅳ and CD44v6 were 11.5%(3/26),11.5%(3/26) and 80.8%(21/26)in the group with lymph node metastasis,and were 69.0%(20/29),55.2%(16/29) and 24.1%(7/29) in the group without lymph node metastasis,respectively.The expression of elastic fibers,collagen type Ⅳ and CD44v6 were significant difference in the two groups with and without lymph node metastasis(P=0.000).There was statistically significant correlation among elastic fibers,collagen type Ⅳ,CD44v6 and lymph node metastasis(all P
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Journal of Chinese Physician
Año:
2000
Tipo del documento:
Article