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Efficacy analysis after surgical treatment for gastric cancer with synchronous hepatic metastases / 中国现代普通外科进展
Article en Zh | WPRIM | ID: wpr-512727
Biblioteca responsable: WPRO
ABSTRACT
Objective:To clarify the indications and efficacy after simultaneous surgical treatment in gastric cancer patients with synchronous hepatic metastases (GCHM).Methods:A total of 21 GCHM patients who underwent D2 gastrectomy with R0 hepatic resection (11 cases) or non-R0 hepatic resection (10 cases) from March 2004 to April 2016 were analyzed retrospectively.The clinicopathological characteristics and survival were compared between the two groups.Results:Cumulative survival rate was improved in R0 hepatic resection group compared with non-R0 hepatic resection group:1-year (54.5% vs 48.0%),2-year(27.3% vs 0%),and 5-year(27.3% vs 0%,P=0.044).The median survival time in R0 hepatic resection group and non-R0 hepatic resection group were 16.2 and 5.9 months (P=0.008).Univariate analysis revealed that Bormann's classification (P=0.010) and state of regional lymph node (P=0.004) were significant predictive factors regarding cumulative survival rate.However,there was no significant prognostic factor (P=0.031) in multivariate analysis might partly owing to interaction among them and/or a small number of patients.Conclusion:Multidisciplinary treatments based on R0 hepatic resection combined with D2 gastrectomy could improve survival in selected GCHM patients.
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Texto completo: 1 Base de datos: WPRIM Tipo de estudio: Prognostic_studies Idioma: Zh Revista: Chinese Journal of Current Advances in General Surgery Año: 2017 Tipo del documento: Article
Texto completo: 1 Base de datos: WPRIM Tipo de estudio: Prognostic_studies Idioma: Zh Revista: Chinese Journal of Current Advances in General Surgery Año: 2017 Tipo del documento: Article