Progress in remodeling and spacing factor-1 in human malignant tumors / 肿瘤研究与临床
Cancer Research and Clinic
; (6): 641-645, 2016.
Article
en Zh
| WPRIM
| ID: wpr-504547
Biblioteca responsable:
WPRO
ABSTRACT
Remodeling and spacing factor-1 (Rsf-1), firstly discovered in 1998 and located in the nucleus, is one of the most commonly amplified gene and its protein molecular weight is about 240 ×103. The interaction between Rsf-1 and human sucrose non-fermenting protein 2 homologue (hSNF2H) changes the cell growth signals and environment, which is inclined to cause the cells loss of the normal regulation, leading to the abnormal proliferation and occurrence of tumors. Recent study has shown that Rsf-1 is closely related to the prognosis of a lot of human malignancies, such as genitourinary system tumors, gastrointestinal tumors, head and neck cancer, non-small cell lung cancer and glioma.
Texto completo:
1
Base de datos:
WPRIM
Tipo de estudio:
Prognostic_studies
Idioma:
Zh
Revista:
Cancer Research and Clinic
Año:
2016
Tipo del documento:
Article