Genetic Polymorphisms of 21 Autosomal STR Loci of Fujian Han Population / 法医学杂志
Journal of Forensic Medicine
; (6): 211-214, 2015.
Article
en Zh
| WPRIM
| ID: wpr-498877
Biblioteca responsable:
WPRO
ABSTRACT
Objective To investigate the genetic polym orphism s of 21 autosom al STR loci of Fujian H an population and evaluate the forensic application value of GlobalFilerTM E xpress kit. Methods A m plified w ith GlobalFilerTM E xpress kit, DNA sam ples were obtained from 741 unrelated individuals of Fujian H an population. The population genetics param eters of 21 autosom al STR loci were calculated. Results The 21 autosom al STR loci were found to be no deviation from Hardy-Weinberg equilibration (P>0.05) and relatively abundant in high polym orphism . H eterozygosity ranged from 0.589 to 0.914, pow er of dis-crim ination ranged from 0.754 to 0.992, polym orphic inform ation content ranged from 0.520 to 0.940, and pow er of exclusion ranged from 0.278 to 0.825. The SE33 locus was the highest degree in poly-m orphism . Conclusion The 21 STR loci of GlobalFilerTM E xpress kit have high value in discrim ination pow er and can be useful in personal identification and paternity test in Fujian H an population.
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Journal of Forensic Medicine
Año:
2015
Tipo del documento:
Article