The role of retinoic acid receptor and its signal pathway in the renal disease / 临床儿科杂志
Journal of Clinical Pediatrics
; (12): 227-231, 2016.
Article
en Zh
| WPRIM
| ID: wpr-487608
Biblioteca responsable:
WPRO
ABSTRACT
Retinoic acid (RA) receptor, is a group of ligand-regulated nuclear transcription factors and widely distributed in various tissue cells. The different subtypes of RA receptor can polymerize into homologous or heterogenous dimmers, and then participate in the physiological and pathological processes of embryonic development, cell proliferation and differentiation, and apoptosis. However, the relationship between the expression of RA receptor and the diseases is different in diverse cells or tissues. Recent researches demonstrated that RA receptor is closely related to the pathogenesis and development of renal diseases. This article aims to review the role of the RA receptor and its signal pathway in the development of renal diseases.
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Journal of Clinical Pediatrics
Año:
2016
Tipo del documento:
Article