Methodological quality assessment of clinical trials on Chinese medicine interventional chemotherapy induced gastrointestinal toxic reactions during 2000-2014 / 重庆医学
Chongqing Medicine
; (36): 3661-3663, 2015.
Article
en Zh
| WPRIM
| ID: wpr-482711
Biblioteca responsable:
WPRO
ABSTRACT
Objective To evaluate the methodological quality of clinical trials on Chinese medicine interventional chemothera-py induced gastrointestinal toxic reactions from 2000 to 2014.Methods The randomized controlled trials(RCT)and semi-RCT on Chinese medicine interventional chemotherapy induced gastrointestinal toxic reactions were retrieved from the China National Knowledge Infrastructure (CNKI),Wanfang databases,VIP,China Biology Medicine Database (CBM)and Traditional Chinese Medicine (TCM)database by computer and supplemented by the manual retrieval (January 2000 to December 2014).The methodo-logical quality assessment on the included RCT and semi-RCT was conducted by using the Cochrane risk assessment table of bias. Results 291 articles were finally screened out,only 76 of RCT and semi-RCT were conformed to the at least one of low risk stand-ards of Cochrane risk assessment table of bias.Therefore the total methodological quality was not good enough.Conclusion The publishing of clinical trials on Chinese medicine interventional chemotherapy induced gastrointestinal toxic reactions shows the in-creasing trend year by year during the past 14 years.However,the different defects exist in the overall trial design.
Texto completo:
1
Base de datos:
WPRIM
Tipo de estudio:
Clinical_trials
/
Guideline
/
Risk_factors_studies
Idioma:
Zh
Revista:
Chongqing Medicine
Año:
2015
Tipo del documento:
Article