Early recognition and treatment of adrenal crisis in children / 中国小儿急救医学
Chinese Pediatric Emergency Medicine
; (12): 672-675, 2015.
Article
en Zh
| WPRIM
| ID: wpr-481565
Biblioteca responsable:
WPRO
ABSTRACT
Adrenal crisis is a life-threatening emergency caused by the destruction or altered function of the adrenal gland with a primary deficit in cortisol secretion(primary adrenal insufficiency)or by hypotha-lamic-pituitary pathologies determining a deficit of adrenocorticotropic hormone(secondary adrenal insuffi-ciency).Infection and abrupt end glucocorticoid treatment are the major precipitating causes of adrenal crisis. Patients with adrenal crisis typically present with hypovolemic shock or hypotension,nausea,vomiting,and fe-ver responding well to parenteral hydrocortisone administration.The main laboratory findings include lower serum cortisol concentrations,hyponatremia,hypoglycaemia and/or hyperkalemia.Delay diagnosis of adrenal insufficiency leads to adrenal crisis which is potentially lethal complication.Empirical glucocorticoid replace-ment should be initiated as soon as the suspicious of adrenal crisis,or sooner if the patient presents in adrenal crisis in critically ill children.
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Pediatric Emergency Medicine
Año:
2015
Tipo del documento:
Article