Antiviral drug screening based on pseudoviruses:research advances / 国际药学研究杂志
Journal of International Pharmaceutical Research
; (6): 316-322, 2015.
Article
en Zh
| WPRIM
| ID: wpr-467825
Biblioteca responsable:
WPRO
ABSTRACT
The pseudotype virus is a virus nucleic acids packaged by another virus envelope protein, to form the virus with the exogenous virus envelope and maintain virus genome characteristics of itself. Due to the loss of its ability to self-replicate and high safety, pseudoviruses are widely used as safe substitutes for infectious virus in virology studies, such as HIV, H5N1 and HCV Here we will introduce the advantages and limitations of pseudoviruses, and through summarizing a large number of research achievements, we prove pseudoviruses are feasible and effective as an antiviral drug screening platform. The platform is safe and reliable and it will make more contribution in antiviral drug research.
Texto completo:
1
Base de datos:
WPRIM
Tipo de estudio:
Diagnostic_studies
/
Screening_studies
Idioma:
Zh
Revista:
Journal of International Pharmaceutical Research
Año:
2015
Tipo del documento:
Article