Effects of 10 % Pentastarch on Hypervolemia and Hemodilution following clipping of cerebral aneurysm / 대한마취과학회지
Korean Journal of Anesthesiology
; : 1265-1270, 1993.
Article
en Ko
| WPRIM
| ID: wpr-46400
Biblioteca responsable:
WPRO
ABSTRACT
Cerebral vasospasm following aneurysmal subarachnoid hemorrhage is one of the most important causes of cerebral ischemia. Hypervolemic hypertension and hemodilution have been reported to be an effective method for prevention and treatment for cerebral ischemia secondary to cerebral vasospasm.We compared the volume expanding effects between normal saline(20 cases), 10% pentastarch(20 cases) and dextran(20 cases) after clipping of cerebral aneurysm in the patients with subarachnoid hemorrhage and the incidence of vasospasm by transcranial doppler(TCD) postoperatively. The results were as follows ;1) The total amount of infused volume in pentastarch and dextran group were 310+/-46ml, 438 +/-262ml respectively,and were significantly smaller than normal saline group, 1078+/-187ml.(p<0.05) 2) Plasma osmolality was increased by 10 mOsm/kg in pentastarch group, but statistically insignificant. 3) Hematocrit value was decreased significantly in pentastarch and dextran group from 34.9+/-1.03%, 34.8+/-1,4% to 31.6+/-1.38%, 31.9+/-0.9% respectively.(p<0.05) 4) Cases over 80cm/sec by TCD were 3 in normal saline, 2 in pentastarch, and 2 in dextran group. We conclude that 10% pentastareh could be used as an effective blood volume expander after cerebral aneurysm clipping.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Concentración Osmolar
/
Plasma
/
Hemorragia Subaracnoidea
/
Volumen Sanguíneo
/
Aneurisma Intracraneal
/
Isquemia Encefálica
/
Incidencia
/
Dextranos
/
Derivados de Hidroxietil Almidón
/
Vasoespasmo Intracraneal
Tipo de estudio:
Incidence_studies
/
Prognostic_studies
Límite:
Humans
Idioma:
Ko
Revista:
Korean Journal of Anesthesiology
Año:
1993
Tipo del documento:
Article