Review on taxanes-induced peripheral neuropathy / 中国生化药物杂志
Chinese Journal of Biochemical Pharmaceutics
; (6): 185-188, 2015.
Article
en Zh
| WPRIM
| ID: wpr-463847
Biblioteca responsable:
WPRO
ABSTRACT
As a tubulin stabilizer, taxanes are widely used in the treatment of breast cancer, ovarian cancer, non-small-cell lung cancer (NSCLC),and part of head and neck malignant tumors, and were confirmed to be significantly effective.However, taxanes-induced peripheral neuropathy(TIPN) still affects the quality of life and psychological status of patients to varying degrees, severe cases can lead to dose reduction, and even chemotherapy interruption.In this paper, we summarize the pathogenesis, risk factors, clinical assessment, the progress of prevention and treatment of TIPN, to provide the basis for the prediction and early prevention of TIPN in the clinical administration, thus we can improve patients’ quality of life while extending their survival.
Texto completo:
1
Base de datos:
WPRIM
Tipo de estudio:
Prognostic_studies
Aspecto:
Patient_preference
Idioma:
Zh
Revista:
Chinese Journal of Biochemical Pharmaceutics
Año:
2015
Tipo del documento:
Article