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Expression of programmed cell death 5 in endometrial adenocarcinoma and its clinical significance / 中国基层医药
Article en Zh | WPRIM | ID: wpr-455134
Biblioteca responsable: WPRO
ABSTRACT
Objective This study was designed to investigate the relationship between programmed cell death 5 (PDCD5) and endometrial carcinoma .Methods 60 tissue samples of endometrial carcinomas ,40 normal proliferative endometrium tissues and 28 endometrial atypical hyperplasia tissues were obtained from patients who underwent operation.The expression of PDCD5 was detected by Real-time PCR and immunohistochemical analysis . Results In normal proliferative endometrium , atypical hyperplasia tissues and endometrial carcinoma , the PDCD5 mRNA was gradually decreased[(1.21 ±0.16),(0.83 ±0.07),(0.42 ±0.02),F=5.637,P0.05). Conclusion PDCD5 might become a potential molecular marker of early diagnosis of endometrial carcinoma .
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Texto completo: 1 Base de datos: WPRIM Tipo de estudio: Screening_studies Idioma: Zh Revista: Chinese Journal of Primary Medicine and Pharmacy Año: 2014 Tipo del documento: Article
Texto completo: 1 Base de datos: WPRIM Tipo de estudio: Screening_studies Idioma: Zh Revista: Chinese Journal of Primary Medicine and Pharmacy Año: 2014 Tipo del documento: Article