Research progress on polyamine metabolism as a target for anti-cancer therapy / 中国肿瘤临床
Chinese Journal of Clinical Oncology
; (24): 597-600, 2014.
Article
en Zh
| WPRIM
| ID: wpr-448491
Biblioteca responsable:
WPRO
ABSTRACT
Rapid tumor cell growth depends on intracellular polyamine levels higher than those of normal cells. Intracellular polyamine depletion inhibits tumor cell proliferation and induces tumor cell apoptosis. Therefore, polyamine metabolism has recently been identified as an important target for anti-tumor therapy. This article briefly summarizes recent polyamine metabolism targeting, polyamine depletion within the tumor cells through a variety of methods, and the antitumor effects of the treatment.
Texto completo:
1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Clinical Oncology
Año:
2014
Tipo del documento:
Article