Sulfasalazine-induced Reversible Leukoencephalopathy
Journal of the Korean Neurological Association
; : 218-221, 2010.
Article
en Ko
| WPRIM
| ID: wpr-43853
Biblioteca responsable:
WPRO
ABSTRACT
A 50-year-old woman presented with a 4-day history of apathy, perseveration, and confusion. These symptoms appeared 16 days after she had started taking sulfasalazine for rheumatoid arthritis. Brain MRI showed bilateral symmetrical discoid lesions involving the corona radiata. She fully recovered 7 days after stopping the medications. Follow-up brain MRI revealed remarkable improvement of the lesions. The pathomechanisms related to sulfasalazine-induced leukoencephalopathy may be demyelinating processes due to impaired T-cell-mediated immunity.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Artritis Reumatoide
/
Sulfasalazina
/
Encéfalo
/
Estudios de Seguimiento
/
Leucoencefalopatías
/
Apatía
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Female
/
Humans
Idioma:
Ko
Revista:
Journal of the Korean Neurological Association
Año:
2010
Tipo del documento:
Article