Mechanisms of immunological rejection in transplantation / 国际外科学杂志
International Journal of Surgery
; (12): 619-621, 2012.
Article
en Zh
| WPRIM
| ID: wpr-420321
Biblioteca responsable:
WPRO
ABSTRACT
Immunological rejection is the major barrier to successful transplantation.The immune response to an allograft is an ongoing dialogue between the innate and adaptive immune system that will lead to the rejection of allograft.Activation of elements of the innate immune system,triggered as a consequence of tissue injury sustained during cell isolation or organ retrieval and ischemia reperfusion,will initiate and amplify the adaptive response.Identifying the molecular pathways that trigger tissue injury,signal transduction and rejection facilitates the identification of targets for the development of immunosuppressants.
Texto completo:
1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
International Journal of Surgery
Año:
2012
Tipo del documento:
Article