Clinical research of severe burn patients with chemical poisoning treatment by continuous renal replacement therapy / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy
; (12): 1480-1482, 2011.
Article
en Zh
| WPRIM
| ID: wpr-412876
Biblioteca responsable:
WPRO
ABSTRACT
Objective To investigate the influence of biochemical indices and coagulation function in severe burn patients with chemical poisoning by continuous renal replacement therapy(CRRT)treatment.Methods 60 patients were randomly divided into CRRT treatment group(n=30)and basic therapy(n=30).The control group received conventional treatment,based therapies in the treatment group based on the use CRRT treatment,the average course of 2 or 3 times to observe the biochemical indicators coagulation,and cytokine before treatment compared with that after treatment.Results In treatment group,the index of heart rate,arterial partial pressure of oxygen,blood urea nitrogen,serum creatinine after treatment[(110.0±26.0)times/min,(93.3±11.0)mm Hg,(6.1 ±1.3)mmol/L,(106.4±24.8)μmol/L],compared with before treatment[(148.0±38.0)times/min、(84.5 9.1)mm Hg,(8.6±1.9)mmol/L,(172.6 ±29.8)μmol/L]were significantly different(t=2.154,2.345、2.458,2.544,all P＜0.05),and compared with control group[(133.0±37.0)times/min,(86.5 ±9.9)mm Hg,(8.3 ±2.0)mmol/L,(134.6±26.8)μmol/L]were statistically significant(t=2.174,2.245,2.558,2.444,all P＜0.05);The index of IL-1,IL-6,IL-8,TNF-α after treatment in treatment group[(260.7 ±25.9)ng/L,(327.6±129.2)ng/L,(300.3±146.6)ng/L,(97.1±22.3)ng/L)compared with control group after treatment[(368 .2±24.8)ng/L,(400.2±198.3)ng/L,(482.9±198.5)ng/L,(225.0 ±22.3)ng/L]had significant differences(t=2.314、2.371、2.278、2.316,all P＜0.05).Conclusion The treatment group of patients with severe burns could remove the inflammatory mediators and cywkines,to improve their inflammatory state and maintain stability in the environment.
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Primary Medicine and Pharmacy
Año:
2011
Tipo del documento:
Article