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Intraperitoneal hyperthermal chemotherapy combined with general chemotherapy after surgery for malignant gastrointestinal tumors / 中华全科医师杂志
Article en Zh | WPRIM | ID: wpr-396084
Biblioteca responsable: WPRO
ABSTRACT
A total of 101 patients undergoing operations for malignant gastrointestinal tumors (stage Ⅱ to Ⅲ) were enrolled and randomly assigned to receive intraperitoneal hyperthermal chemotherapy plus intravenous chemical injection (treatment group, n=51) or routine intravenous chemical injection (control group, n=50). Our results indicated that the recurrence rate and the metastatic rate in the treatment group were significantly lower than those in the control group (25.5% vs. 50.0%, 13.7% vs. 30.0%, both P< 0. 05), although the 3-and 5 year-survival rates were significantly higher (both P < 0. 05). Our data suggest that intraperitaneal hyperthermal chemotherapy plus general chemotherapy after surgery for malignant gastrointestinal tumors could effectively reduce tumor recurrence and metastases and improve long-term survival.
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Texto completo: 1 Base de datos: WPRIM Idioma: Zh Revista: Chinese Journal of General Practitioners Año: 2009 Tipo del documento: Article
Texto completo: 1 Base de datos: WPRIM Idioma: Zh Revista: Chinese Journal of General Practitioners Año: 2009 Tipo del documento: Article