High mobility group box 1 and central nervous system disease / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
; (12): 797-800, 2009.
Article
en Zh
| WPRIM
| ID: wpr-392331
Biblioteca responsable:
WPRO
ABSTRACT
High mobility group box 1 (HMGB 1 ) is a family member of the high mobility group. HMGB1 binds to cell surface specific receptor-receptor for advanced glycation end products (RAGE) and toll-like receptor 2 (TLR2), and thus it exhibits extensive biological activities. HMGB1 participates in pathophysiological processes including inflammatory response and regulation of blood-brain barrier permeability in central nervous system, arid it is closely correlated with the diseases such as ischemia stroke, Alzheimer's disease and gliocytoma.
Texto completo:
1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
International Journal of Cerebrovascular Diseases
Año:
2009
Tipo del documento:
Article