Effects of cyclosporine A on the expressions of MMP-2 and MMP-9 in the heart of streptozocin-induced diabetic rats / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
; (12): 238-240, 2010.
Article
en Zh
| WPRIM
| ID: wpr-390308
Biblioteca responsable:
WPRO
ABSTRACT
The effects of cyclosporine A on matrix metalloproteinases(MMP)-2 and-9 expressions in the cardiac muscle of streptozocin-induced diabetic rats were investigated.The expressions of MMP-2 and MMP-9 mRNA and proteins in the cardiac muscle of diabetic rats were significantly upregulated,which could be decreasedby cyclosporine A(P＜0.05 or P＜0.01).The results suggest that cyclosporine A may effectively ameliorate the injuries of diabetic cardiomyopathy.
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1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Endocrinology and Metabolism
Año:
2010
Tipo del documento:
Article