Roles of periostin in cancer / 国际肿瘤学杂志
Journal of International Oncology
; (12): 92-96, 2011.
Article
en Zh
| WPRIM
| ID: wpr-384216
Biblioteca responsable:
WPRO
ABSTRACT
Periostin, a extracellular matrix protein structurally similar to fasciclin proteins, is expressed specifically in various tumor tissues and correlates with tumor progression and prognosis. Periostin prevents the apoptosis of tumor cells, promotes tumor growth and can induce angiogenic signaling cascades through αvβ3-FAK and Flk-1/KDR. It also contributes to epithelial-mesenchymal-transformation promoting tumor invasion and metastasis. Periostin maybe a potential therapeutic target of cancer treatment.
Texto completo:
1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
Journal of International Oncology
Año:
2011
Tipo del documento:
Article