The Safety of Long-Term Ingestion of Fucoidan from Gagome Kombu (<i>Kjellmaniella Crassifolia</i>) on Cancer Patients / 日本補完代替医療学会誌
Japanese Journal of Complementary and Alternative Medicine
; : 17-24, 2013.
Article
en Ja
| WPRIM
| ID: wpr-376365
Biblioteca responsable:
WPRO
ABSTRACT
<b>Objective:</b> Fucoidan, a sulfated polysaccharide in Gagome kombu (GKF) is known to exhibit immune-enhancing and anti-cancer activities. Recently, cancer patients use various dietary supplements containing fucoidan and mushroom extracts. However, there have been few reports on the safety and efficacy of fucoidan-containing supplements. In this study, we examined the safety of long-term ingestion of GKF in cancer patients.<br> <b>Methods:</b> Twenty six (26) Japanese cancer patients—16 of whom (male 6, female 10, age 62.8 ± 10.7) have completed cancer treatment and 10 (male 4, female 6, 67.0 ± 10.6) still under treatment and regularly taking anti-cancer drugs and hormone pills—were chosen to ingest GKF-containing supplements (200–300 mg/day) for 8 weeks. Before ingestion and every 4 weeks thereafter (4<sup>th</sup> and 8<sup>th</sup> week), blood chemistry analysis, hematological analysis, urinalysis and immune analysis were conducted.<br> <b>Result:</b> There were no adverse clinical changes in blood and urinary analysis. In addition, no serious adverse effects were observed.<br> <b>Conclusion:</b> These results indicate long-term ingestion of GKF is indeed, safe for cancer patients.<br>
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Base de datos:
WPRIM
Idioma:
Ja
Revista:
Japanese Journal of Complementary and Alternative Medicine
Año:
2013
Tipo del documento:
Article