Acute Lymphoblastic Leukemia in Elderly Patients: A Single Institution's Experience
The Korean Journal of Internal Medicine
; : 328-339, 2011.
Article
en En
| WPRIM
| ID: wpr-35155
Biblioteca responsable:
WPRO
ABSTRACT
BACKGROUND/AIMS: We investigated the clinical characteristics and prognosis of elderly patients with acute lymphoblastic leukemia (ALL). METHODS: We reviewed the clinical data, laboratory findings, bone marrow findings, and cytogenetic analysis of elderly patients (> or = 60 years) with ALL, and data of an additional 101 younger adult patients ( or = 60 years) and 101 younger adult patients ( or = 60 years) was 10.3 months (p = 0.003). In the elderly patients with ALL, T cell lineage and the presence of lymphadenopathy were significant prognostic factors for OS in a univariate analysis (p = 0.033 and 0.041, respectively). CONCLUSIONS: The outcomes of Korean elderly patients with ALL were poor, and the shorter OS was mainly due to the low CR rate. T-cell lineage and the presence of lymphadenopathy were significant prognostic factors in Korean elderly patients with ALL.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Factores de Tiempo
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Examen de la Médula Ósea
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Inducción de Remisión
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Cromosoma Filadelfia
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Distribución de Chi-Cuadrado
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Modelos Logísticos
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Modelos de Riesgos Proporcionales
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Tasa de Supervivencia
/
Estudios Retrospectivos
/
Factores de Riesgo
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
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Adult
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Aged
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Aged80
/
Female
/
Humans
/
Male
País/Región como asunto:
Asia
Idioma:
En
Revista:
The Korean Journal of Internal Medicine
Año:
2011
Tipo del documento:
Article