Acute hyperammonemic encephalopathy after 5-fluorouracil based chemotherapy
Annals of Surgical Treatment and Research
; : 179-182, 2016.
Article
en En
| WPRIM
| ID: wpr-34974
Biblioteca responsable:
WPRO
ABSTRACT
5-Fluorouracil (5-FU) based chemotherapy has been commonly used to treat metastatic or advanced colon cancer as an adjuvant chemotherapy. Although the side effects of 5-FU such as gastrointestinal problems and neutropenia and thrombocytopenia are common, not many cases of 5-FU related encephalopathy are reported. Hyperammonemic encephalopathy is a rare central nervous system toxicity following 5-FU chemotherapy manifesting as altered mental status with elevated ammonia levels with no radiologic abnormality. We report one case of 5-FU induced hyperammonemic encephalopathy occurring after Folfox4 (oxaliplatin, folinic acid and 5-fluorouracil) chemotherapy in a colon cancer patient who presented with confused mental status soon after the chemotherapy and review the 5-FU related encephalopathy.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Trombocitopenia
/
Encefalopatías Metabólicas
/
Sistema Nervioso Central
/
Leucovorina
/
Quimioterapia Adyuvante
/
Neoplasias del Colon
/
Hiperamonemia
/
Quimioterapia
/
Fluorouracilo
/
Amoníaco
Límite:
Humans
Idioma:
En
Revista:
Annals of Surgical Treatment and Research
Año:
2016
Tipo del documento:
Article