Research progress on human acute leukemia xenograft mouse models / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 555-559, 2014.
Article
en Zh
| WPRIM
| ID: wpr-349671
Biblioteca responsable:
WPRO
ABSTRACT
The methods for modeling human acute leukemia in mice include xenotransplantation of human leukemia cells, retroviral transduction/transplantation, transgenesis, chemical mutagenesis and insertional mutagenesis. Establishing human acute leukemia mouse models through xenograft is an important way to study acute leukemia. This review focuses on the newest progress of studies on human acute leukemia xenograft mouse models in the regards of the immunodeficiency mouse, preconditioning, cytokines, cell transplantation, the evaluation and application of model.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Leucemia
/
Enfermedad Aguda
/
Modelos Animales de Enfermedad
/
Xenoinjertos
Límite:
Animals
/
Humans
Idioma:
Zh
Revista:
Journal of Experimental Hematology
Año:
2014
Tipo del documento:
Article