Thrombosis and morphology of plaque rupture using optical coherence tomography / 中华医学杂志(英文版)
Chinese Medical Journal
; (24): 1092-1095, 2013.
Article
en En
| WPRIM
| ID: wpr-342233
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>BACKGROUND</b>Thrombosis following plaque rupture is the main cause of acute coronary syndrome, but not all plaque ruptures lead to thrombosis. There are limited in vivo data on the relationship between the morphology of ruptured plaque and thrombosis.</p><p><b>METHODS</b>We used optical coherence tomography (OCT) to investigate the morphology of plaque rupture and its relation to coronary artery thrombosis in patients with coronary heart disease. Forty-two patients with coronary artery plaque rupture detected by OCT were divided into two groups (with or without thrombus) and the morphological characteristics of ruptured plaque, including fibrous cap thickness and broken cap site, were recorded.</p><p><b>RESULTS</b>The fibrous cap of ruptured plaque with thrombus was significantly thinner compared to caps without thrombus ((57.00 ± 17.00) µm vs. (96.00 ± 48.00) µm; P = 0.0076).</p><p><b>CONCLUSIONS</b>Plaque rupture associated with thrombosis occurs primarily in plaque covered by a thin fibrous cap. Thick fibrous caps are associated with greater stability of ruptured plaque.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Rotura Espontánea
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Diagnóstico por Imagen
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Angiografía Coronaria
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Tomografía de Coherencia Óptica
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Síndrome Coronario Agudo
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Placa Aterosclerótica
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Métodos
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
Idioma:
En
Revista:
Chinese Medical Journal
Año:
2013
Tipo del documento:
Article