Experimental study on attachment of bacillus Calmette-Guerin to bladder wall with different types of injury / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
; (6): 65-67, 2004.
Article
en Zh
| WPRIM
| ID: wpr-341940
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate whether different types of injury on bladder wall can influence bacillus Calmette-Guerin (BCG) attachment.</p><p><b>METHODS</b>The bladder mucosa of 24 rabbits were treated by electrocautery,cryocautery and incision on left lateral wall, right lateral wall and posterior wall, respectively. Then radiolabeled BCG ((3)H-BCG) was instilled into bladder. Two hours latter, the injured bladder wall with different methods and non-injured wall (anterior wall of bladder) were surgically removed and digested. The quantity of BCG of each specimen was determined by liquid scintillation counter.</p><p><b>RESULT</b>The quantity of BCG attachment to bladder wall with different injuries was significantly higher than that of non-injured wall (P<0.001), meanwhile there was no statistically difference among the BCG levels of different injury types (P>0.05).</p><p><b>CONCLUSION</b>BCG attachment is not influenced by different types of injury on the bladder wall.</p>
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Base de datos:
WPRIM
Asunto principal:
Fisiología
/
Heridas y Lesiones
/
Vejiga Urinaria
/
Adhesión Bacteriana
/
Microbiología
/
Mycobacterium bovis
Límite:
Animals
Idioma:
Zh
Revista:
Journal of Zhejiang University. Medical sciences
Año:
2004
Tipo del documento:
Article