Effect of preemptive analgesia with flurbiprofen axetil on patient-controlled intravenous analgesia with tramadol in patients undergoing postburn plastic surgery / 南方医科大学学报
Journal of Southern Medical University
; (12): 1255-1256, 2009.
Article
en Zh
| WPRIM
| ID: wpr-336095
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To observe the preemptive analgesic effect of flurbiprofen axetil for post-operative pain relief.</p><p><b>METHODS</b>Sixty ASA class I or II patients undergoing postburn plastic surgery were randomly assigned into two groups to receive intravenous administration of 100 mg flurbiprofen axetil (group F, n=30) and 10 ml intravenous saline (group C, n=30) 30 min before surgery. After the operation, all the patients received patient-controlled intravenous analgesia (PCIA) with tramadol for pain relief. The postoperative analgesic effect was assessed by visual analog scales (VAS) at 1, 2, 4, 8, 12 and 24 h after surgery, with tramadol requirements and the adverse effects were recorded.</p><p><b>RESULT</b>At 1, 2, 4, and 8 h after the operation, the patients in group F showed significantly lowered VAS scores as compared with the patients in group C (P<0.05). The requirement of tramadol was also significantly less in group F than in group C (182.9-/+37.4 vs 227.3-/+49.8 mg, P<0.05). No significant difference was found in the adverse effects between the two groups.</p><p><b>CONCLUSION</b>Flurbiprofen axetil can produce preemptive analgesia and reduce the tramadol dose during postoperative PCIA in patients undergoing postburn plastic operations.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Dolor Postoperatorio
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Cirugía General
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Cirugía Plástica
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Factores de Tiempo
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Tramadol
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Quemaduras
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Antiinflamatorios no Esteroideos
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Flurbiprofeno
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Analgesia Controlada por el Paciente
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Usos Terapéuticos
Límite:
Adult
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Journal of Southern Medical University
Año:
2009
Tipo del documento:
Article