Effects of HCMV on phenotypes of parotid duct epithelial cells and its mechanisms / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
; (6): 132-134, 2005.
Article
en Zh
| WPRIM
| ID: wpr-333082
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effects of HCMV infection on phenotypes of parotid duct epithelial cells and relative mechanisms.</p><p><b>METHODS</b>The expressions of immediate early antigen of HCMV, pan cytokeratin and cathepsin D etc. were detected by immunohistochemical staining in tissues of parotid cytomegalic inclusion disease.</p><p><b>RESULTS</b>Cytokeratin which acts as an epithelial marker became negative while staining of Cathepsin D was intensified in parotid duct epithelial cells after infected by HCMV.</p><p><b>CONCLUSION</b>It demonstrated that cytokeratin was lost through over-expression of Cathepsin D in parotid duct epithelial cells infected by HCMV.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Patología
/
Fisiología
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Vimentina
/
Virología
/
Inmunohistoquímica
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Antígenos de Diferenciación Mielomonocítica
/
Antígenos CD
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Catepsina D
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Infecciones por Citomegalovirus
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Conductos Salivales
Límite:
Animals
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Chinese Journal of Experimental and Clinical Virology
Año:
2005
Tipo del documento:
Article