Epidemiological study of thalasaemia among children in Xishuangbanna, Dehong and Nujiang of Yunnan province / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
; (6): 579-582, 2011.
Article
en Zh
| WPRIM
| ID: wpr-326886
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the carrier rate of thalasaemia among the children of 10 minority ethnic groups in 3 border states (Xishuangbanna, Dehong and Nujiang) of Yunnan Province.</p><p><b>METHODS</b>A total of 6562 samples of children under 10 years old were analyzed by blood cell automatic analysis and hemoglobin electrophoresis.</p><p><b>RESULTS</b>The overall carrier frequency of thalasaemia was highest (46.2%) in Dehong, and lowest (30.6%) in Nujiang. The carrier frequency of beta-thalasaemia was the highest (40.6%) in Achang, and lowest (2.5%) in Dulong. The carrier frequency of alpha-thalasaemia was the highest (22.1%) in Dai from Xishuangbanna, followed by Dulong (19.1%).</p><p><b>CONCLUSION</b>Thalasaemia carrier rates were high among the children of 10 minority ethnic groups in Yunnan. There were regional differences in their incidences. The results provide a valuable basis for thalasaemia prevention in Yunnan minorities in the three border states.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Talasemia
/
Hemoglobinas Anormales
/
China
/
Epidemiología
/
Prevalencia
/
Talasemia beta
/
Talasemia alfa
/
Etnología
/
Genética
/
Grupos Minoritarios
Tipo de estudio:
Prevalence_studies
Aspecto:
Determinantes_sociais_saude
Límite:
Child
/
Child, preschool
/
Humans
/
Infant
/
Newborn
País/Región como asunto:
Asia
Idioma:
Zh
Revista:
Chinese Journal of Medical Genetics
Año:
2011
Tipo del documento:
Article