Study of genetic polymorphism of 6 short tandem repeat loci in Nongqu Mongolian of inner Mongolia Autonomous Region in China / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
; (6): 222-223, 2005.
Article
en Zh
| WPRIM
| ID: wpr-321119
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To get the genotype and allele frequency distribution of 6 short tandem repeat (STR) loci VWA, FGA, PENTAE, D6S1043, D2S1772, D7S3048 in NongQu Mongolia of China.</p><p><b>METHODS</b>Two hundred and ninety-three unrelated individuals from Nongqu Mongolian were investigated. Polymerase chain reaction and polyacrylamide gel electrophoresis were used.</p><p><b>RESULTS</b>Eighty alleles and 335 genotypes were detected, with frequencies ranging from 0.0017 to 0.2828. All the 6 loci met Hardy-Weinberg equilibrium. The statistical analysis of 6 STR loci showed the heterozygosity (H) >/= 0.7945, the discrimination power (DP) >/= 0.9160, the probability of paternity exclusion (PPE) >/= 0.5919, and the polymorphic information content (PIC) >/= 0.7617.</p><p><b>CONCLUSION</b>These results could serve as valuable data to enrich the Chinese genetic database and play an important role in Chinese population genetic forensic medical application.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Polimorfismo Genético
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Desequilibrio de Ligamiento
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China
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Reacción en Cadena de la Polimerasa
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Repeticiones de Microsatélite
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Electroforesis en Gel de Poliacrilamida
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Alelos
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Frecuencia de los Genes
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Genética
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Genotipo
Límite:
Humans
País/Región como asunto:
Asia
Idioma:
Zh
Revista:
Chinese Journal of Medical Genetics
Año:
2005
Tipo del documento:
Article