Effect of Ningzhi capsule on blood lipid spectrum in type 2 diabetes mellitus patients complicated with hyperlipidemia / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
; (12): 118-121, 2008.
Article
en Zh
| WPRIM
| ID: wpr-315213
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To observe the effect of Ningzhi Capsule (NZC) on blood lipid spectrum in type 2 diabetes mellitus patients complicated with hyperlipemia (DM-HL).</p><p><b>METHODS</b>Adopting randomized, parallel and controlled trail method, a total of 70 DM-HL patients of qi-yin deficiency and phlegm-blood stagnant syndrome type were randomized into two groups. The original medication for lowering blood sugar and blood pressure was unchanged, the trial group received oral administration of NZC 5 tablets, 3 times a day, while the control group received Lipanthgl or Simvastatin depending on their different constituents of blood lipids. After 6 months of treatment, sixty subjects completed the trail while two patients dropped out due to side effect and 8 patients lost follow-up (4 in each group). Levels of blood lipids, blood routine, liver and kidney function and symptoms in patients were detected and compared.</p><p><b>RESULTS</b>After treatment, levels of total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL-C), apoprotein B, and lipoprotein a (LPa) lowered, while levels of high-density lipoprotein (HDL-C) and apoprotein A raised in the trial group as compared with those before treatment (P < 0.05, P < 0.01), but showed no difference between the two groups after treatment except HDL level (P > 0.05). Scores of symptoms were also lowered significantly in the trial group (P < 0.01). In the observation period, no abnormal findings in blood and urine routine examination as well as in liver and renal function were found.</p><p><b>CONCLUSION</b>NZC could lower the blood lipid spectrum and improve the TCM symptoms in DM-HL patients without any adverse reaction.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Sangre
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Cápsulas
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Medicamentos Herbarios Chinos
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Deficiencia Yin
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Resultado del Tratamiento
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Usos Terapéuticos
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Diabetes Mellitus Tipo 2
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Diagnóstico Diferencial
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Quimioterapia
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Hiperlipidemias
Tipo de estudio:
Clinical_trials
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Diagnostic_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Chinese Journal of Integrated Traditional and Western Medicine
Año:
2008
Tipo del documento:
Article