Treatment of refractory severe autoimmune disease by combined therapy with Chinese drug and autohemopoietic stem cell transplantation / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
; (12): 212-215, 2008.
Article
en Zh
| WPRIM
| ID: wpr-315165
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinical effect of Chinese herbal medicine combined with auto-hemopoietic stem cell transplantation for refractory severe autoimmune disease (RSAID).</p><p><b>METHODS</b>Auto-hemopoietic stem cell transplantation was conducted for the treatment of 7 patients with RSAID, including 4 cases of systemic lupus erythematosus (SLE), 2 myasthenia gravis (MG) and 1 polymyositis (PM) with the FAC program (consisting of fludarabine, antithymocyte globulin, and cyclophosphamide FAC) as for pretreatment. Traditional Chinese medicine (TCM) was given orally after transplantation to patients according to their syndrome type.</p><p><b>RESULTS</b>The hemopoiesis function was smoothly re-established in all patients, with their clinical symptoms and signs obviously improved, laboratory indexes negatively conversed or obviously decreased, and withdrawal or dose reducing of medicines.</p><p><b>CONCLUSION</b>Combined use of TCM after auto-hemopoietic stem cell transplantation can accelerate patients' hemopoiesis function re-establishment, with significant effects in reducing complications, improving clinical symptoms and signs.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Enfermedades Autoinmunes
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Terapéutica
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Trasplante Autólogo
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Vidarabina
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Medicamentos Herbarios Chinos
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Resultado del Tratamiento
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Terapia Combinada
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Trasplante de Células Madre Hematopoyéticas
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Usos Terapéuticos
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Quimioterapia Combinada
Límite:
Adolescent
/
Adult
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Chinese Journal of Integrated Traditional and Western Medicine
Año:
2008
Tipo del documento:
Article