Interdigitating dendritic cell sarcoma/tumor: a study of 3 cases / 中华病理学杂志
Chinese Journal of Pathology
; (12): 676-679, 2008.
Article
en Zh
| WPRIM
| ID: wpr-315115
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the pathologic features, diagnosis and differential diagnosis of interdigitating dendritic cell sarcoma (IDCS).</p><p><b>METHODS</b>The clinical findings, morphologic features and immunophenotype of 3 cases of IDCS were investigated.</p><p><b>RESULTS</b>Gross examination showed that IDCS had a greyish-white to greyish-yellow cut surface. The site of occurrence included lung, spleen (with lymph node metastasis) and lymph node. Histologically, the tumor cells were arranged in nests, fascicles and whorls, with intimate admixture of many lymphocytes and plasma cells. They were oval to spindle in shape and contained pale eosinophilic cytoplasm, oval and sometimes grooved nuclei, small distinct nucleoli and ill-defined cell borders. Immunohistochemical study showed that the tumor cells expressed S-100 protein.</p><p><b>CONCLUSIONS</b>IDCS is a rare type of histiocytic and dendritic cell malignancy with distinctive morphologic findings. It needs to be distinguished from follicular dendritic cell sarcoma, inflammatory pseudotumor, Langerhans' cell histiocytosis, malignant melanoma, undifferentiated carcinoma and anaplastic large cell lymphoma. Immunohistochemical staining for S-100 protein is helpful in confirming the diagnosis.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Patología
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Células Dendríticas
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Carcinoma
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Proteínas S100
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Diagnóstico
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Diagnóstico Diferencial
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Alergia e Inmunología
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Sarcoma de Células Dendríticas Foliculares
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Sarcoma de Células Dendríticas Interdigitantes
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Ganglios Linfáticos
Tipo de estudio:
Diagnostic_studies
Límite:
Adolescent
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Chinese Journal of Pathology
Año:
2008
Tipo del documento:
Article