Meta-analysis on comparison of long-term complications and quality of life between two digestive tract reconstruction techniques following total gastrectomy / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
; (12): 135-139, 2013.
Article
en Zh
| WPRIM
| ID: wpr-314840
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To compare the incidence of postoperative long-term complications and quality of life between two digestive tract reconstruction techniques after total gastrectomy in order to provide evidence for clinical practice.</p><p><b>METHODS</b>A systematic literature search was carried out to obtain studies of randomized controlled trials (RCTs) of reconstruction techniques including jejunal interposition and Roux-en-Y. Data extracted from RCTs for meta-analysis were independently assessed by two reviewers. A meta-analysis was performed by RevMan5.0 software.</p><p><b>RESULTS</b>A total of 1628 gastric cancer cases undergoing total gastrectomy from 10 RCTs were eligible for inclusion, among whom 728 received jejunal interposition reconstruction and 954 Roux-en-Y anastomosis. As compared with Roux-en-Y anastomosis, jejunal interposition reconstruction significantly decreased the incidence of dumping syndrome (OR=0.19, 95%CI:0.11-0.34, P<0.01), increased the prognostic nutritional index (WMD=6.02, 95%CI:1.82-10.22, P<0.01), and improved the body weight postoperatively (WMD=-2.45, 95%CI:-3.81--1.71, P<0.01). Meanwhile, jejunal interposition reconstruction did not prolong operative time and hospital stay (both P>0.05).</p><p><b>CONCLUSION</b>Jejunal interposition has better efficacy than Roux-en-Y in dumping syndrome and quality of life, and is a reasonable and effective digestive tract reconstruction for long-term survival of gastric cancer patients.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Complicaciones Posoperatorias
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Calidad de Vida
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Neoplasias Gástricas
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Cirugía General
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Anastomosis en-Y de Roux
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Ensayos Clínicos Controlados Aleatorios como Asunto
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Gastrectomía
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Yeyuno
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Métodos
Tipo de estudio:
Clinical_trials
/
Systematic_reviews
Aspecto:
Patient_preference
Límite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Gastrointestinal Surgery
Año:
2013
Tipo del documento:
Article