1059 g/c gene polymorphism of C-reactive protein in patients with deep vein thrombosis / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 769-771, 2011.
Article
en Zh
| WPRIM
| ID: wpr-313898
Biblioteca responsable:
WPRO
ABSTRACT
This study was aimed to investigate the distribution of 1059 G/C gene polymorphism of C-reactive protein(CRP) in deep vein thrombus (DVT) and its clinical significance. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used to screen 1059 G/C polymorphism in exon 2 of C-reactive protein gene in 61 cases of DVT and 60 healthy controls. The frequency of mutation was calculated. The results showed that there was no statistical difference of 1059 G/C genotype and mutation frequency of allele between deep vein thrombosis group and control group (p > 0.05). It is concluded that the 1059 G/C gene polymorphism of CRP displays certain difference in races and areas, and whether 1059 G/C gene polymorphism of CRP is a dangerous factor for deep vein thrombosis, which needs to be deeply explored.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Polimorfismo de Longitud del Fragmento de Restricción
/
Proteína C-Reactiva
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Estudios de Casos y Controles
/
Exones
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Trombosis de la Vena
/
Frecuencia de los Genes
/
Genética
/
Genotipo
Tipo de estudio:
Observational_studies
Límite:
Adolescent
/
Adult
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Aged
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Aged80
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Journal of Experimental Hematology
Año:
2011
Tipo del documento:
Article